Among Seattle's prominent annual fairs and festivals are the 24-day Seattle International Film Festival, Northwest Folklife over the Memorial Day weekend, numerous Seafair events throughout July and August (ranging from a Bon Odori celebration to the Seafair Cup hydroplane races), the Bite of Seattle, one of the largest Gay Pride festivals in the United States, and the art and music festival Bumbershoot, which programs music as well as other art and entertainment over the Labor Day weekend. All are typically attended by 100,000 people annually, as are the Seattle Hempfest and two separate Independence Day celebrations. Other significant events include numerous Native American pow-wows, a Greek Festival hosted by St. Demetrios Greek Orthodox Church in Montlake, and numerous ethnic festivals (many associated with Festál at Seattle Center).

There are other annual events, ranging from the Seattle Antiquarian Book Fair & Book Arts Show; an anime convention, Sakura-Con; Penny Arcade Expo, a gaming convention; a two-day, 9,000-rider Seattle to Portland Bicycle Classic, and specialized film festivals, such as the Maelstrom International Fantastic Film Festival, the Seattle Asian American Film Festival (formerly known as the Northwest Asian American Film Festival), Children's Film Festival Seattle, Translation: the Seattle Transgender Film Festival, the Seattle Gay and Lesbian Film Festival, and the Seattle Polish Film Festival.

The Henry Art Gallery opened in 1927, the first public art museum in Washington. The Seattle Art Museum (SAM) opened in 1933; SAM opened a museum downtown in 1991 (expanded and reopened 2007); since 1991, the 1933 building has been SAM's Seattle Asian Art Museum (SAAM). SAM also operates the Olympic Sculpture Park (opened 2007) on the waterfront north of the downtown piers. The Frye Art Museum is a free museum on First Hill. Regional history collections are at the Loghouse Museum in Alki, Klondike Gold Rush National Historical Park, the Museum of History and Industry and the Burke Museum of Natural History and Culture. Industry collections are at the Center for Wooden Boats and the adjacent Northwest Seaport, the Seattle Metropolitan Police Museum, and the Museum of Flight. Regional ethnic collections include the Nordic Heritage Museum, the Wing Luke Asian Museum and the Northwest African American Museum. Seattle has artist-run galleries, including 10-year veteran Soil Art Gallery, and the newer Crawl Space Gallery.
The Seattle Great Wheel, one of the largest Ferris wheels in the U.S., opened in June 2012 as a new, permanent attraction on the city's waterfront, at Pier 57, next to Downtown Seattle. The city also has many community centers for recreation, including Rainier Beach, Van Asselt, Rainier, and Jefferson south of the Ship Canal and Green Lake, Laurelhurst, Loyal Heights north of the Canal, and Meadowbrook.

Woodland Park Zoo opened as a private menagerie in 1889, but was sold to the city in 1899. The Seattle Aquarium has been open on the downtown waterfront since 1977 (undergoing a renovation 2006). The Seattle Underground Tour is an exhibit of places that existed before the Great Fire.

Since the middle 1990s, Seattle has experienced significant growth in the cruise industry, especially as a departure point for Alaska cruises. In 2008, a record total of 886,039 cruise passengers passed through the city, surpassing the number for Vancouver, BC, the other major departure point for Alaska cruises.